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Search results for "Xgeva"

Key safety concerns with Denosumab ( Xgeva ) included in the Warnings and Precautions section of the existing product labeling involve the risks of osteonecrosis of the jaw ( ONJ ) and hypocalcemia. O ...


Denosumab ( Prolia ) is a human monoclonal antibody ( IgG2 ) that targets and binds with high affinity and specificity to RANKL, preventing activation of its receptor, RANK, on the surface of osteocla ...


Atypical femoral fractures have been reported rarely in patients with postmenopausal osteoporosis receiving long-term ( greater than or equal to 2.5 years ) treatment with Denosumab 60 mg ( Prolia ) i ...


The Food and Drug Administration ( FDA ) has expanded the use of Xgeva ( Denosumab ) to treat adults and some adolescents with giant cell tumor of the bone ( GCTB ), a rare and usually non-cancerous t ...