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Increased risk for skin lesions with low-dose exposure to Arsenic in drinking water

Reminyl appears to protect against nerve agents

Increased risk for non-Hodgkin lymphoma with regular use of COX-2 inhibitors

Diabetes: Exubera, no evidence available of an additional therapeutic benefit

Vioxx: heart attack can occur within the first two weeks of use

Drug-induced hepatotoxicity: Paracetamol and Telithromycin

Trauma intensive care unit: corticosteroids associated with poor outcomes, death

Postmenopausal women at increased risk for cardiovascular disease: Raloxifene associated with increased risk of stroke mortality

Aspirin reduces cardiovascular risks in men and women, but differently

Ketek linked to two cases of liver failure and implicated in a third case of hepatitis

Breakthrough tumor pain: effectiveness of Fentanyl lozenges

FDA has approved a combination of Topotecan and Cisplatin in advanced cervical carcinoma

FDA has approved Wellbutrin XL in patients with history of seasonal affective disorder

Exelon for treatment of dementia linked to Parkinson’s disease

FDA has approved Atripla, an once-a-day three-drug combination in HIV-1 infection

Lucentis in wet age-related macular degeneration, FDA approved

Chromacine may cause serious adverse events

Heart attack: thrombolitic therapy before angioplasty or stent placement not beneficial

Pain in newborn infants: Morphine and topical Tetracaine found effective

Sensible metabolic differences in how adults, infants and children process drugs

Prevention of invasive breast cancer: Evista as effective as Nolvadex

NICE, preliminary recommendations: inhaled Insulin is not recommended for the treatment of type 1 or type 2 diabetes mellitus

Dacogen for treatment of myelodysplastic syndromes, FDA approved

Europe: Herceptin for early-stage in HER2-positive breast cancer

FDA has approved the reintroduction of Tysabri in relapsing multiple sclerosis

Sprycel in chronic myeloid leukemia and Ph+ acute lymphoblastic leukemia, FDA approved

Protopic and Elidel: boxed warning about a possible risk of cancer

Antibiotics: Ketek linked to severe hepatotoxicity

FDA has approved Sutent in GIST and advanced kidney cancer

Inhaled powder form of recombinant human Insulin, Exubera approved by FDA

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