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Methylene Blue, serious CNS reactions possible when given to patients taking serotonergic psychiatric medications

Linezolid, serious CNS reactions possible when given to patients taking serotonergic psychiatric drugs

Smoking cessation drug: monitor patients taking Varenicline for behavior and mood changes

Trajenta for treatment of diabetes mellitus type 2 approved in Europe

FDA moves to limit the amount of Paracetamol to no more than 325 mg in each tablet or capsule

Chantix, a smoking cessation drug, linked to a 72% increased risk of adverse cardiovascular reactions

Children exposed in utero: Valproate, Valproic acid and Divalproex sodium linked to risk of impaired cognitive development

Congenital factor XIII deficiency: Factor XIII Concentrate for the prophylactic treatment

2011 - Fluoroquinolones: risk of QT interval prolongation

Lurasidone for the treatment of schizophrenia

Patients with idiopathic growth hormone deficiency and idiopathic or gestational short stature treated with rhGH during childhood: possible increased risk of death

Zortress to prevent organ rejection in adult kidney transplant recipients, FDA approved

Zometa: safety

Tribenzor, a three-in-one combination product for the treatment of hypertension

Edoxaban versus Enoxaparin in preventing venous thromboembolism after total knee replacement

Diabetes mellitus: FDA has restricted access to Avandia

Advanced non small cell lung cancer with EGFR activating mutations: Erlotinib first-line nearly triples progression free survival

MetMAb combined with Erlotinib in high MET expressing non-small cell lung cancer

Non-Hodgkin’s lymphoma: GA101, the first type II, glycoengineered anti-CD20 monoclonal antibody, demonstrates promising efficacy

FDA has begun process to remove breast cancer indication from Avastin label

Osteoporosis: atypical femur fractures associated to bisphosphonate use

Provenge, the first autologous cellular immunotherapy for patients with prostate cancer

PLX4032 selectivity blocks RAF/MEK/ERK signaling pathway

No benefit of prescription omega-3 fatty acids in prevention of recurrent symptomatic atrial fibrillation in affected patients

Anacetrapib significantly raises HDL cholesterol, cuts LDL cholesterol nearly in half

Afinitor in advanced renal cell carcinoma after failure of treatment with Sunitinib or Sorafenib

Osteoarthritis of the knee or hip: Samyr should not be routinary

Painful neuropathy or chronic pain: Duloxetine treatment

Cystic fibrosis: no benefit or harm with Vitamin-D supplementation

Moderate-level evidence of efficacy and safety for Orencia in rheumatoid arthritis

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